okay here's my advice to make your experience a pleasurable one:
1. Always choose Blanche FIRST. You are in for HELL if you pick Fabienne!
2. Grind your health/stamina/speed stats out with Blanche until they are maxed out.
3. For Fabienne, try staying down the bottom of the screen when she gets irate. Make quick sweeps of the floor for any friendship points that spawn at the middle/top, then quickly get back down to the bottom of the room or she will grind you out of existence.